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C12 NBD dihydro Ceramide (d18:0/12:0)
品牌： Cayman
产品货号： 10008097-10 mg
规格： 10 mg

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折后价：

数量： - +
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  • 产品名称:
    C12 NBD dihydro Ceramide (d18:0/12:0)
  • 别名:
    NBD Cer(d18:0/12:0)|NBD Ceramide (d18:0/12:0)
  • 产品描述:
    Ceramidase catalyzes the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Three isoforms of ceramidases (acid, neutral, and alkaline) have been characterized based on differences in their catalytic pH optimum.{9268,10050} C12 NBD dihydro ceramide is a fluorescent ceramide analog that contains a saturated bond in the C-4/C-5 position of the sphingosine backbone. C-12 NBD ceramide, which contains the C-4/C-5 double bond, is a fluorescent ceramidase substrate that can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources.{14063} C12 NBD dihydro ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C-4/C-5 sphingosine bond in C-16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate.{14071} However, experimental characterization of C12 NBD dihydro ceramide as a ceramidase substrate needs to be performed.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    661.9
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • CAS号:
    474943-05-0
  • 分子式:
    C36H63N5O6
  • 溶解度:
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