产品描述:
β-Estradiol 17-valerate is a synthetic estrogen.{58709,58710,58711} It increases estrogen receptor β (ERβ), but not ERα, levels in the hippocampus and cortex of ovariectomized rats when administered at a dose of 0.3 mg/day.{58709} Intradermal administration of β-estradiol 17-valerate (5 µg/animal) induces transient permanent diestrus and decreases litter size in rats.{58710} β-Estradiol 17-valerate has been used to induce polycystic ovarian syndrome in rats.{58711} It has been found in wastewater effluent.{58712} Formulations containing β-estradiol 17-valerate have been used in hormone replacement therapy and in the treatment of menopausal symptoms, as well as in oral contraceptives in combination with dienogest.