产品描述:
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); Item No. 10007945) that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) (Item No. 62570). In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation.{36119} Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers.{18300,18298,18299} Sphinganine can block protein kinase C activation in some cases but not others.{18301,15200} [Matreya, LLC. Catalog No. 1845]