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C18 Ceramide-d7 (d18:1-d7/18:0)
品牌: Cayman
产品货号: 22788-500 µg
规格: 500 µg

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    C18 Ceramide-d7 (d18:1-d7/18:0)
  • 别名:
    C18 Ceramide-d7|Ceramide-d7 (d18:1-d7/18:0)|Cer-d7 (d18:1-d7/18:0)|N-Stearoyl-D-Sphingosine-d7
  • 产品描述:
    C18 Ceramide-d7 is intended for use as an internal standard for the quantification of C18 ceramide (Item No. 19556) by GC- or LC-MS. C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.{40029} Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.{13918} It is selectively down-regulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.{40030}
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    573
  • 产品形式:
    A solution in methanol:chloroform (10:90)
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥99% deuterated forms (d1-d7)
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  • CAS号:
    1840942-14-4
  • 分子式:
    C36H64D7NO3
  • 溶解度:
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