产品描述:
Equilenin is an equine estrogen found in the urine of pregnant mares.{40235} Unlike naturally occurring human estrogens, equilenin has no effect on nitric oxide synthase (eNOS) activity or expression and does not increase production of nitric oxide (NO). It is metabolized to 4-hydroxyequilenin, a carcinogenic compound that induces transformation of C3H 10T½ murine fibroblasts.{40236} Formulations containing equilenin conjugates have been widely used as hormone replacement therapies for post-menopausal women.