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Betamethasone 21-phosphate (sodium salt hydrate)
品牌： Cayman
产品货号： 29778-1 g
规格： 1 g

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折后价：

数量： - +
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  • 产品名称:
    Betamethasone 21-phosphate (sodium salt hydrate)
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  • 产品描述:
    Betamethasone 21-phosphate is a synthetic glucocorticoid.{48966} It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.{48967} Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively.{48968} It increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 µg/kg.{48966} Betamethasone 21-phosphate increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks.{48969} Formulations containing betamethasone 12-phosphate and betamethasone acetate have been used in the treatment of severe allergic conditions and a variety of immune-related conditions.
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  • 保存温度:
    -20
  • 运输温度:
    -20
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  • 预期分子量:
    516.4
  • 产品形式:
    A crystalline solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • 分子式:
    C22H28FO8P • 2Na [XH2O]
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