产品描述:
Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 (Item No. 90420). LXB4 is a positional isomer of LXA4 (Item No. 90410) produced by the metabolism of 15-HETE (Item No. 34700) or 15-HpETE (Item No. 44720) by human leukocytes.{369,350} At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.{16457}