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Sulfatide (bovine) (sodium salt)
品牌： Cayman
产品货号： 24323-50 mg
规格： 50 mg

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数量： - +
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  • 产品名称:
    Sulfatide (bovine) (sodium salt)
  • 别名:
    3-O-Sulfogalactosylceramide|Galactosylceramide I3-sulfate|Ganglioside SM4|I3SO3-GalCer|SM4|Sulfated Galactocerebroside
  • 产品描述:
    Sulfatide are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system.{40646} They are produced from the combination of ceramide and UDP-galactose in the endoplasmic reticulum followed by sulfation in the Golgi apparatus. The ceramide portion contains variable fatty acid chain lengths, which are tissue- and pathology-dependent. Sulfatide are primarily found in the myelin sheath of oligodendrocytes and Schwann cells, with smaller chain lengths predominant during development and longer chain lengths predominant in mature cells.{40648} They accumulate in the lysosome of patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency.{40650,40646} Sulfatide are also located in pancreatic β-cells and inhibit insulin release from isolated rat pancreatic islet cells, suggesting a potential role in diabetes.{40644} Sulfatides can induce inflammation in glia in vitro and certain sulfatides, such as C24:1 3’-sulfo-galactosylceramide, can induce an immune response in vitro in mouse splenocytes.{40645,40651} This product contains sulfatide molecular species with primarily C24:1 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1049]
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    830.1
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • 分子式:
    C42H80NO11S • Na (for stearoyl)
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