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C6 NBD Sphingomyelin (d18:1/6:0)
品牌： Cayman
产品货号： 24328-1 mg
规格： 1 mg

报价：
折后价：

数量： - +
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  • 产品名称:
    C6 NBD Sphingomyelin (d18:1/6:0)
  • 别名:
    NBD SM(d18:1/6:0)|NBD Sphingomyelin (d18:1/6:0)|N-hexanoyl-NBD Sphingosylphosphorylcholine
  • 产品描述:
    C6 NBD sphingomyelin is a biologically active derivative of sphingomyelin (Item Nos. 22674 | 24345) that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; Item No. 18871) group. C6 NBD sphingomyelin has been used to study the metabolism and transport of sphingomyelins.{38317,39498} It is degraded in the plasma membrane to C6 NBD ceramide (Item No. 62527) by neutral sphingomyelinase, an enzyme with three-fold higher activity in undifferentiated HT29 cells than in differentiated cells.{38317} Unlike endogenous long-chain sphingomyelin and C6 sphingomyelin, C6 NBD sphingomyelin can be transported to the cell surface even in the presence of the vesicular transport inhibitor brefeldin A (Item No. 11861), but this transport can be blocked by multidrug resistance protein inhibitors in CHO cells.{39498} This product is a mixture of the D-erythro and L-threo isomers of sphingomyelin. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1912]
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    740.9
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • CAS号:
    94885-04-8
  • 分子式:
    C35H61N6O9P
  • 溶解度:
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