产品描述:
Sphingosine-d9 is intended for use as an internal standard for the quantification of sphingosine (Item No. 10007907) by GC- or LC-MS. Sphingosine is formed primarily from the breakdown of ceramide.{13592} Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628} [Matreya, LLC. Catalog No. 2079]