产品描述:
Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay).{36308,36309} Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment.{36311} Formulations containing fluorometholone have been used for the treatment of eye inflammation.