产品描述:
Ginsenoside Rg1 is a steroid glycoside that has been found in P. ginseng and has diverse biological activities.{64376,64377,64378,64379} In vivo, ginsenoside Rg1 (10, 20, and 40 mg/kg) decreases blood glucose, IL-1β, and IL-18 levels, increases insulin secretion, and inhibits hepatic and pancreatic activation of the NLRP3 inflammasome in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104).{64376} It facilitates fear extinction and decreases immobility time in the tail-suspension and forced swim tests in a mouse model of single-prolonged stress-induced post-traumatic stress disorder (PTSD).{64377} Ginsenoside Rg1 decreases hepatic alanine transaminase (ALT) and aspartate aminotransferase (AST) levels and attenuates hepatic steatosis in a mouse model of ethanol-induced hepatitis.{64378} It also decreases the abundance of Bacteroidetes in the large intestine, cortical neuron apoptosis, and latency to the platform in the Morris water maze in a tree shrew model of Alzheimer’s disease induced by amyloid-β (25-35) (Aβ (25-35)).{64379}