产品描述:
Arachidonoyl glycine (N-arachidonyl glycine; NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA; anandamide),{9578} from extracts of mammalian brain,{9579,9589} and has also been synthesized as an analog of AEA for structure/activity testing.{9580} NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments.{9578,9579,9589} Since it seems to be a very poor ligand for the CB1 receptor,{9580} these effects are probably mediated via other signaling pathways.