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C18 Ganglioside GM3-d3 (d18:1/18:0-d3) (ammonium salt, synthetic)
品牌： Cayman
产品货号： 39226
规格： 250 µg

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数量： - +
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  • 产品名称:
    C18 Ganglioside GM3-d3 (d18:1/18:0-d3) (ammonium salt, synthetic)
  • 别名:
    C18 GM3-d3|Monosialoganglioside GM3-d3|N-Stearoyl Monosialoganglioside GM3-d3|N-ω-CD3-Octadecanoyl monosialoganglioside GM3
  • 产品描述:
    C18 Ganglioside GM3-d3 (d18:1/18:0-d3) is intended for use as an internal standard for the quantification of ganglioside GM3 (Item No. 15587) by GC- or LC-MS. Ganglioside GM3 is a simple monosialoganglioside that demonstrates both antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.{25490,25485} When used at a concentration of 20 μM, it suppresses angiogenesis and reduces endothelial cell proliferation and migration by inhibiting VEGFR2 and Akt phosphorylation.{25490} Furthermore, ganglioside GM3 has been shown to induce the dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance.{25481} This product is fully synthetic and has no variations in the fatty acyl chain or sphingoid backbone. It is intended for use as an analytical standard for the quantification of C18 Ganglioside GM3 by mass spectrometry.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1201.6
  • 产品形式:
    A film
  • 存储溶液:
  • 有效期:
    1095
  • 产地:
    美国
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  • 纯度:
    ≥99% deuterated forms (d1-d3)
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  • CAS号:
    2692623-85-9
  • 分子式:
    C59H104D3N2O21 • NH4
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