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C18 Ganglioside GM2-d7 (d18:1/18:0-d7) (ammonium salt, synthetic)
品牌: Cayman
产品货号: 39641
规格: 250 µg

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    C18 Ganglioside GM2-d7 (d18:1/18:0-d7) (ammonium salt, synthetic)
  • 别名:
    C18 GM2-d7|Monosialoganglioside GM2-d7|N-omega-CD7-Octadecanoyl monosialoganglioside GM2|N-Stearoyl Monosialoganglioside GM2-d7
  • 产品描述:
    C18 Ganglioside GM2-d7 (d18:1/18:0-d7) is intended for use as an internal standard for the quantification of C18 ganglioside GM2 by GC- or LC-MS. C18 Ganglioside GM2 is a monosialylated ganglioside found in the mammalian brain where it is localized to the cell membrane.{40894} It accumulates in Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively.{40891} Ganglioside GM2 disrupts the function of immune cells and, when used at a concentration of 25 µM, increases migration and invasion of SK-RC-45 cells with no effect on proliferation.{39686} This product is fully synthetic and has no variations in the fatty acyl chain or sphingoid backbone. It is intended for use as an analytical standard for the quantification of C18 ganglioside GM2 by GC-MS.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1408.8
  • 产品形式:
    A solution in methanol
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥99% deuterated forms (d1-d7)
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  • 分子式:
    C67H113D7N3O26 • NH4
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