产品描述:
DSPE-PEG(2000) Cyanur is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of micro RNA (miRNA) in vitro.{51713} LNPs containing DSPE-PEG(2000) cyanur, encapsulating let-7a miRNA, and conjugated to the Eph tyrosine kinase receptor (Eph) ligand ephrin-A1 reduce the proliferation and colony formation and size of NCI H2081, NCI 5380, and A549 lung cancer cells, as well as reduce migration of NCI 5380 cells in a wound healing assay.