产品描述:
Pentanoic acid-d9 is intended for use as an internal standard for the quantification of pentanoic acid by GC- or LC-MS. Pentanoic acid is a short-chain saturated fatty acid. It is a gut microbiota metabolite and has also been found in the essential oil of V. alliariifolia and in goat milk.{69307},{52058,52057} Pentanoic acid (0.85 mM) inhibits the proliferation, migration, and invasion of Hep3B, SNU-449, and HepG2 liver cancer cells.{69308} It increases survival and prevents increases in peripheral blood levels of IL-6, TNF-α, and malondialdehyde (MDA) in irradiated mice, as well as prevents decreases in colon length in a mouse model of colitis induced by dextran sodium sulfate (DSS; Item No. 23250), when administered at a concentration of 0.3 mg/ml in the drinking water.{69309} Fecal levels of pentanoic acid are increased in patients with colorectal cancer.{69307}