产品描述:
SIL lipid is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro.{67735} LNPs containing SIL lipid and encapsulating siRNA targeting mRNA encoding the purinergic P2X7 receptor decrease protein levels of the purinergic P2X7 receptor, reduce migration in a wound healing assay, and induce apoptosis and necrosis in 4T1 breast cancer cells.