产品描述:
Phytosphingosine-d7 is intended for use as an internal standard for the quantification of phytosphingosine by GC- or LC-MS. Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans.{39177,39179} It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid (Item No. 22679) as an intermediate.{39084} Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors (mAChRs).{39105} It is essential in the heat stress response in S. cerevisiae.{13592}