产品描述:
Eriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity.{47241,47242,47243,47244,47245} Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 µM and enhances the effect of α-tocopherol (Item No. 25985) on lipid peroxidation.{47242} It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 µmol/kg, indicating a reduction in lipid peroxidation.{47243} Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; Item No. 89540) in rat liver when administered at a dose of 600 mg/kg prior to exercise.{47244} It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 µM, respectively, for human recombinant receptors).{47245}