产品描述:
Bafilomycin B1 is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.{20718,20721,20720,60646,52993,60645} It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner.{60646} Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells.{52993} It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM.{20720} Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.{60645}