产品描述:
Nalidixic acid is a quinolone antibiotic.{41042} It is active against E. coli, Pasturella, K. pneumoniae, A. aerogenes, Proteus, Salmonella, and Shigella with minimum bacteriostatic concentrations (MBCs) ranging from 0.5 to 25 µg/ml. Nalidixic acid increases survival in mouse models of systemic K. pneumoniae, A. aerogenes, Proteus, or Salmonella infection (ED50s = 60, 35, 50, and 62 mg/kg, respectively). Formulations containing nalidixic acid have previously been used in the treatment of urinary tract infections.