产品描述:
PCI 24781 is an HDAC inhibitor that predominantly targets HDAC1 with a Ki value of 7 nM.{32732} It inhibits HDAC2, HDAC3/SMRT, HDAC6, HDAC8, and HDAC10 with Ki values of 19, 8.2, 17, 280, and 24 nM, respectively.{32732} PCI 24781 can prevent the growth of tumor cells in vitro, inducing apoptosis, as well as in mice harboring HCT116 or DLD-1 colon tumor xenografts.{32732}