产品描述:
Cordycepin is a nucleoside analog originally isolated from C. militaris that has diverse biological activities.{65548,22954,65547,65545,65546} Upon entry into cells, it is converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis.{22954} It incorporates into DNA and RNA at internal and terminal positions in SK-HEP-1 cells.{65547} Cordycepin (0.1-1 mg/ml) is active against B. subtilis.{65548} It increases IL-10 secretion and mRNA expression in isolated human peripheral blood mononuclear cells (PBMCs) when used at a concentration of 24 µg/ml.{65545} Cordycepin (1 mg/kg per day) increases survival of mice infected with C. albicans or C. krusei.{65546}