产品描述:
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.{22577,22591} DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM.{22586} It is approximately 10-fold less potent against PARP2.{22587} DPQ can be used in either cells or in animals.{22588,22589}