产品描述:
Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases.{22863,7777} Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 µM.{22863,22860} It also blocks caspase-mediated apoptosis in vivo.{22858} Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.{22859}