产品描述:
Gossypol is a racemic mixture of natural polyphenols isolated from parts of the cotton plant (genus Gossypium). It causes infertility in a variety of cotton pests and spermatogenesis arrest in humans.{23003} Gossypol also has antimalarial properties, preventing the growth of P. falciparum at low micromolar concentrations.{23001} It inhibits aldose reductase (Ki = 0.5 µM).{23002} Gossypol also acts as an anticancer agent, inhibiting cell growth in various cancer cell lines, in part by blocking the anti-apoptotic functions of Bcl-2 and Bcl-xL, again at low micromolar concentrations.{23000}