产品描述:
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 µM).{31547} It does not bind to bromodomains of BRD4, BRD9, or CREBBP.{31547} CeMMEC13 synergizes with (+)-JQ1 (Item No. 11187) to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.{31547}