产品描述:
Flunixin is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 (IC50s = 3.24 and 0.55 µM, respectively).{48282} It inhibits carrageenan-induced prostaglandin E2 (PGE2; Item No. 14010) and thromboxane B2 (TXB2; Item No. 19030) production in sheep exudate and serum, respectively, when administered at a dose of 1.1 mg/kg.{48283} Flunixin (1.1 mg/I/kg) has anti-inflammatory, analgesic, and antipyretic activity in horses.{48284} Formulations containing flunixin have been used in the veterinary treatment of pain and fever in livestock.