产品描述:
Madrasin is a cell-permeant inhibitor of pre-mRNA splicing.{34068} It interferes with the early stages of spliceosome assembly and stalls spliceosome assembly at the A complex.{34068} Madrasin induces cell cycle arrest, promotes a specific reorganization of subnuclear protein localization, and modulates splicing of multiple pre-RNA species in both HeLa and HEK293 cells when used at lower concentrations.{34068}