产品描述:
TFMB-R-2-HG is a cell-permeable form of (R)-2-hydroxyglutarate ((R)-2-HG).{42076} (R)-2-HG is structurally similar to α-ketoglutarate and competitively inhibits α-ketoglutarate-dependent dioxygenases, including lysine demethylases and DNA hydroxylases.{26775,26774,26769} TFMB-R-2-HG has been used to assess the role of (R)-2-HG in leukemogenesis.{42076}