产品描述:
Ganoderic acid C1 is a triterpenoid that has been found in G. lucidum and has diverse biological activities.{48842,58313,58311,58312} It inhibits angiotensin-converting enzyme (ACE; IC50 = 745 µM).{58313} Ganoderic acid C1 also inhibits HIV-1 protease with an IC50 value of 180 µM.{48842} It reduces the proliferation of murine Lewis lung carcinoma cells but not murine Meth-A sarcoma cells (EC50s = 17 and >20 µg/ml, respectively).{58311} Ganoderic acid C1 (20 µg/ml) inhibits LPS-induced NF-κB phosphorylation and production of TNF-α in RAW 264.7 cells, as well as in peripheral blood mononuclear cells (PBMCs) isolated from patients with asthma.{58312}