产品描述:
Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes).{46138} It also inhibits ACAT in J774 macrophages (IC50 = 0.46 μM) without affecting cell growth.