产品描述:
6-hydroxy Warfarin is a metabolite of (+)-warfarin (Item No. 13526), which is a weaker vitamin K antagonist than (-)-warfarin (Item No. 13531).{34754,34753,17423} Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9); however, stereoselective metabolism also occurs, with CYP1A1 and CYP1A2 primarily responsible for metabolism of (+)-warfarin to 6-hydroxy warfarin.{34754,34753}