产品描述:
Toloxatone is an inhibitor of monoamine oxidase A (MAO-A; Ki = 1.8 µM).{61267} It is selective for MAO-A over MAO-B (Ki = 44 µM). Toloxatone (100 mg/kg) inhibits deamination of serotonin (5-HT) and norepinephrine in rat brain.{61268} It also decreases immobility time in the forced swim test in mice when administered at a dose of 256 mg/kg.{61269}