产品描述:
Resibufogenin is a cardiac glycoside first isolated from Bufonis venom that acts as an inhibitor of the Na+/K+-ATPase.{32254} It exhibits cardiotonic, vasopressor, and respiratory stimulating actions in both animal and clinical models.{32253} Resibufogenin has been used to antagonize the action of marinobufagenin in a rat experimental model of preeclampsia.{32255} Resibufogenin is also reported to have antiproliferative effects against cancer cells, inducing cell cycle arrest by suppressing the expression of cyclin D1.{32252}