产品描述:
Syringaldehyde is a polyphenol that has been found in E. granulatus and has diverse biological activities.{57598,57599,57600,57601} It inhibits LPS-induced COX-2 activity in RAW 264.7 cells with an IC50 value of 19.23 µM.{57598} Syringaldehyde inhibits the proliferation of HCT116, Caco-2, and HT-29 colon cancer cells (IC50s = 56.3, 35.9, and 68.6 µM, respectively).{57599} It decreases plasma glucose levels in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104) when administered at doses ranging from 1.8 to 7.2 mg/kg.{57600} Syringaldehyde (25 and 50 mg/kg) reduces infarct size in a rat model of myocardial infarction induced by isoproterenol (Item No. 15592).{57601}