产品描述:
Nelfinavir is an orally bioavailable inhibitor of the HIV-1 protease (Ki =2 nM).{24362} It demonstrates anti-cancer activity, selectively preventing the growth of HER2-positive breast cancer cells in vitro by inhibiting Hsp90 (IC50 = 3.1 μM).{24361} Formulations containing nelfinavir have been used in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.