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Cobaltic(III) Protoporphyrin IX Chloride
品牌: Cayman
产品货号: 33794-10 mg
规格: 10 mg

报价:
折后价:

数量: - +
产品详情
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  • 产品名称:
    Cobaltic(III) Protoporphyrin IX Chloride
  • 别名:
    Cobaltic Protoporphyrin IX Chloride
  • 产品描述:
    Cobaltic(III) protoporphyrin IX chloride is a metalloporphyrin and an inducer of heme oxygenase-1 (HO-1) activity.{60523} Unlike other metalloporphyrins, cobaltic(III) protoporphyrin IX chloride induces activity of HO-1, the rate-limiting enzyme in heme catabolism, in vitro and in vivo.{60523,60524} It also reduces the activity of δ-aminolevulinate synthase, the enzyme that catalyzes the rate-limiting step of heme biosynthesis, as well as decreases the activity of cytochrome P450 (CYP), in rat liver microsomes ex vivo when administered at a dose of 125 µmol/kg.{60524} Cobaltic(III) protoporphyrin IX chloride (5 mg/kg) prevents liver injury and increases in the percentage of hepatic apoptotic cells in a mouse model of liver ischemia-reperfusion injury.{60525} It increases survival and decreases the number of lung colony forming units (CFUs) in mice infected with Y. pestis at the same dose.{60526} Cobaltic(III) protoporphyrin IX chloride has also been used as a catalyst for the electrochemical reduction of carbon dioxide in carbon electrodes.{60527}
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    655
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
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  • 纯度:
    ≥95%
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  • CAS号:
    102601-60-5
  • 分子式:
    C34H30ClCoN4O4 • 2H
  • 溶解度:
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