产品描述:
Ricinine is a piperidine alkaloid that has been found in R. communis and has diverse biological activities.{61796,61797,61798,61799} It is an inhibitor of acetylcholinesterase (AChE; IC50 = 54.5 µg/ml).{61797} It scavenges ABTS (Item No. 27317) radicals and chelates iron (IC50s = 102.65 and 104.32 µg/ml, respectively). Ricinine is toxic to adult A. gambiae when used at a concentration of 0.04 mg/ml in a feeding assay.{61798} It is also toxic to mice with an intraperitoneal LD50 value of 340 mg/kg but an oral LD50 value of 3,000 mg/kg.{61796} It has been used as a biomarker of ricin poisoning.{61799}