产品描述:
Carbaryl-d7 is intended for use as an internal standard for the quantification of carbaryl (Item No. 24139) by GC- or LC-MS. Carbaryl is a carbamate insecticide.{39792} It is an inhibitor of acetylcholinesterase (AChE; IC50 = 13.6 nM for the mosquito enzyme). Carbaryl is toxic to fourth instar mosquito larvae (LC50 = 0.83 ppm) and tobacco budworms (LD50 = 0.3 mg/g).{72127,72128} In vivo, carbaryl (30 mg/kg per day) increases the serum levels of IL-4 and IL-10 and decreases serum levels of IL-2, IFN-γ, IL-1β, and TNF-α, spleen and thymus weight, as well as increased lymphocyte proliferation induced by concanavalin A (Item No. 14951), in rats.{39794} Formulations containing carbaryl have been used to control insects in agriculture.