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trans-Indole-3-acrylic acid
品牌： Adipogen
产品货号： AG-CR1-3677-G001
规格： 1 g

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折后价：

数量： - +
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  • 产品名称:
    trans-Indole-3-acrylic acid
  • 别名:
    IAcrA; trans-3-Indoleacrylic acid; trans-beta-Indoleacrylic acid; (E)-3-(1H-Indol-3-yl)acrylic acid; NSC29428; NSC137806; BRN0006317
  • 产品描述:
    Inflammation suppressor. Tryptophan metabolite produced by human microbiota (intestinal commensale Peptostreptococcus sp.). Involved in keeping the intestinal barrier intact and works as anti-inflammatory molecule. Patients with Inflammatory Bowel Disease (IBD) have an altered microbiota, with less Peptostreptococcus sp. and therefore reduced production of trans-indole-3-acrylic acid. Chromophoric L-Trp analog used to probe the allosteric properties of the internal aldimine of tryptophan synthase. Also shown to be a moderate inhibitor of tryptophan synthase, trypothan-2,3-dioxygenase (TDO), indoleamine-2,3-dioxygenase (IDO), L-dopachrome isomerase and xanthine oxidase. Reagent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize and analyze polyphenols and synthetic polymers. Used as heterocyclic building block or intermediate for the synthesis of indolyl acrylamide-derived inhibitors, pharmaceuticals or agrochemicals.
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  • 保存温度:
    +4°C
  • 运输温度:
    Ambient
  • 细胞定位:
  • 预期分子量:
    187.2
  • 产品形式:
    solid
  • 存储溶液:
  • 有效期:
    Stable for at least 2 years after receipt when stored at +4°C.
  • 产地:
    瑞士
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  • 纯度:
    >98%
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  • CAS号:
    29953-71-7
  • 分子式:
    C11H9NO2
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