产品描述:
N6-Cyclopentyladenosine is a selective agonist at adenosine 1 receptors (A1Rs) (Kis = 2.3, 790, and 43 nM for A1R, A2R, and A3R receptors, respectively, in transfected CHO cells).{34118,27925} When microinjected into the rat brainstem, it increases blood pressure and heart rate.{34115} It is effective for pain in normal and nerve-injured rats and shows anticonvulsant activity in a rat model of generalized seizures.{34116,34117}