产品描述:
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}