产品描述:
Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Item No. 16681), and a derivative of prostaglandin F2α (PGF2α; Item Nos. 16010 | 16020).{11931} It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered unoprostone (1.2, 3.6, or 6 µg/µl) prevents constant light-induced degradation of photoreceptors in rats.{67580}