产品描述:
Eledoisin is an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist originally isolated from E. moschata.{46470,46472} It binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum, respectively), and NK3 receptors (pD2 = 7.11 and 7.06 in isolated rat portal vein and hamster urinary bladder, respectively).{46471} Eledoisin induces contraction of isolated guinea pig ileum and rabbit jejunum.{41381} It also induces salivation in rats and lowers arterial blood pressure in rabbits and guinea pigs in vivo.{41381,46473}