产品描述:
15(S)-Latanoprost is a 15(S) isomer of the FP receptor agonist latanoprost (Item No. 16812) in which the carbon 15 hydroxyl is inverted relative to latanoprost.{9736} Topical administration of 15(S)-latanoprost (3 µg/eye) reduces intraocular pressure (IOP) in cynomolgus monkeys and does not induce eye irritation in cats. The free acid form of 15(S)-latanoprost induces relaxation in isolated cat iris sphincter muscles (IC50 = 24 nM). 15(S)-Latanoprost is a potential impurity in commercial preparations of latanoprost.{72411}