产品描述:
Taprostene is a stable prostacyclin (PGI2) analog and agonist of the prostacyclin receptor, IP. It does not activate the PGE2 receptor EP4,{15488} which, like IP, promotes vascular smooth muscle relaxation when stimulated. Taprostene has been used extensively to study the role of the IP receptor in tissue preparations{15488,17478} and in vivo.{15995,17479} It has also been used in the screening and evaluation of potential IP antagonists.{15914}