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Histrelin (acetate)
品牌: Cayman
产品货号: 23663-5 mg
规格: 5 mg

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    Histrelin (acetate)
  • 别名:
    [(ImBzl)-d-His6,Pro9-NET]-LHRH|[Des-Gly10,D-His(Bzl)6,Pro-NHEt9]-LHRH|[Des-Gly10,D-His(Bzl)6]-LHRHethyl amide
  • 产品描述:
    Histrelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor (GNRHR; Ki = 0.2 nM in CHO cells expressing the human receptor).{36464} It stimulates release of oxytocin (Item No. 11799) and vasopressin ex vivo from the isolated rat hypothalamo-neurohypophysial system at a concentration of 100 nM.{36469,36470} In vivo, the initial dose of histrelin (100 μg) stimulates acute increases in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone serum levels (50-, 2.5-, and 15-fold, respectively), while chronic treatment leads to 95% decreases in LH and FSH responses in rhesus monkeys.{36471} Formulations containing histrelin have been used in the treatment of advanced prostate cancer and central precocious puberty.
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  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    1323.5
  • 产品形式:
    A crystalline solid
  • 存储溶液:
  • 有效期:
    1460
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  • 纯度:
    ≥98%
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  • CAS号:
    220810-26-4
  • 分子式:
    C66H86N18O12 • XC2H4O2
  • 溶解度:
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