产品描述:
Mestranol is a semisynthetic estrogen prodrug of ethynyl estradiol (Item No. 10006486), an estrogen receptor agonist.{41236} It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response.{41237} Formulations containing mestranol were previously used as oral contraceptives.